Thermal Fogging Disinfection

Thermal fogging is the process by which disinfectant solution is suspended within the air for a period of time in order to disinfect the surfaces of dust particles and inaccessible parts of a building. It is the last, but most important, stage of any complete biosecurity cleaning and disinfection programme, playing a major role in disease prevention and control.


Hyperox™ has been independently tested for use in thermal fogging, under the requirements of the AFNOR test method NFT 72-281 (1986) for ‘Thermonebulisation’. The data demonstrates the efficacy of Hyperox™  with an in-use concentration of 1.7ml/m3 using different types of thermal fogging machine. Always follow the good practices recommended in the section titled ‘Thermal Fogging Machine Operation’.



The total airspace volume of a given building is the floor area multiplied by the average height.


For a pitched roof building, an average height is determined by measuring from the floor (point A in the diagram below), to halfway between the top of the buildings wall (point B), and the apex of the roof (point C): The table below indicates the volume of Hyperox™ concentrate and water required to achieve effective thermal fogging within a given size of building:

Total Airspace Volume (m3) Volume of Hyperox™ concentrate (litres) to achieve 1:10 dilution Volume of water to be added to concentrate (litres)
100 m3


200 m3
0.34 3.4
500 m3
0.85 8.5
1000 m3
1.70 17.0
2500 m3
4.25 42.5
3000 m3
5.10 51.0
3500 m3
5.95 59.5
4000 m3
6.80 68.0


Fill the thermal fogging machine reservoir tank(s) with the appropriate volume of prepared Hyperox™ solution.


Direct the nozzle of the fogger into the building through a suitable aperture (with the air intake of the fogger situated outside of the building) and activate the motor. Allow the thermal fogging procedure to run until the reservoir tank(s) are empty. Switch off and remove the fogging machine at the end of the cycle and then close the aperture. Leave the building closed for a minimum of 30 minutes and then ventilate for at least a further 30 minutes prior to re-entering.


Do not leave the thermal fogging machine filled with disinfectant after use. Thoroughly clean it each time after use by running it for a minimum of 30 seconds with clean water in the reservoir tank(s), then empty the tank(s) ready for future use.


Proper attention to after use cleaning of the thermal fogging machine will help to prevent the corrosion of susceptible metal components and help to prolong its working life.

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