用于制药和生物技术行业的离子交换树脂和吸附剂
Lewatit®离子交换树脂和吸附剂，广泛应用于生物加工和生物技术、制药、生物制药、营养保健品和食品等行业的各种应用中。它们的最终产品涵盖范围甚广，从食品和动物饲料，到药品中使用的活性药物成分（API）。离子交换树脂和吸附剂，通过提供捕获、纯化（包括精细纯化）、和色谱分析的支持，或通过其在生物分子的解毒、转化、脱色或脱盐等方面的应用，帮助处理和清洁从生物质中获得的产品。因此除了用于清洁外，离子交换树脂还有助于稳定氨基酸、蛋白质、维生素、生物碱等产品和其他活性成分。此外，离子交换树脂已被确立为以传统或研磨形式输送活性物质的基材。酶催化反应也可以在固定酶的帮助下进行，因此离子交换树脂作为基质为催化过程提供了许多好处。
在制药和生物加工行业的制造过程中，需要不同水质的水作为溶剂。不同类型的Lewatit®离子交换树脂可以组合以达到有益的效果，从而满足必定会用到的工艺水软化或脱盐的不同质量要求。朗盛的
LewaPlus®设计软件可以在量身定制的基础上对各种组合进行建模，从而为用户提供获得最佳解决方案的最大信心。它还可以通过可靠和彻底的操作来处理生产设施的废水。
对于这些和其他应用，朗盛提供一系列特殊的离子交换树脂，可根据特定要求进行定制。现在就找到最适合您需求的产品吧。
Antibiotics are derived from fermentation or chemical synthesis. Lewatit® resins and adsorbents are utilized in capture and purification, e.g., within cephalosporine, streptomycin, gentamycin, neomycin, erythromycin, and vancomycin production.
Supported processes are various, ranging from isolation (e.g., Lewatit® VP OC 1064 MD PH, Lewatit® PH 8021), decolorization (e.g., Lewatit® PH 7061), conversion (e.g., Lewatit® PH 1061, Lewatit® PH 7061), demineralization and polishing (e.g., Lewatit® PH 3021).
Amino acids are the building blocks of proteins and play a key role in the existence of living organisms. They are produced in bioreactors by bacterial fermentation of carbohydrates. Industrial purification of most types of amino acids often involves ion exchange resins and adsorbents steps.
They can be separated from each other by strong acidic cation exchange resins (e.g., Lewatit® PH 2061 MDS), captured from a complex fermentation broth mixture by separation from non-ionic impurities (e.g., Lewatit® PH 1061, Lewatit® PH 5021) and decolorized (Lewatit® VP OC 1064 MD PH). Selection of resin types is based on type and charge of amino acid.
Lewatit® supports the production of amino acids, ranging from BCAA’s (branched-chain amino acids) to unbranched ones, such as lysin, threonine, tryptophane, histidine, arginine, serine, and many more.
A large selection of marketed pharmaceuticals is based on polysaccharides, and derive either from fermentation pro¬cesses or natural extracts. One well known product class originating from animal source are GAG’s (glycosylated amino glycans), such as heparin, chondroitin, nadroparin, dermatan and others as well. Their capture and purification is typically done with ion exchange resins (Lewatit® PH 1074 HEP) to allow high yield, activity, and purity of end products.
An important feature of resin involves a specially designed macroporous structure to allows best conditions for adsorption and desorption. Lewatit® PH 1074 HEP is added to the digestion mixture, takes up the GAG and is finally separated from solution. Afterwards elution of, e.g., heparin, from ion exchange resin is done with brine.
