State-of-the-Art High-Pressure Laboratory & Hydrogenation Expertise
From lab-scale development to industrial-scale productionAt Saltigo, we offer cutting-edge infrastructure and deep expertise to support the development and scale-up of high-pressure chemical processes — with a particular focus on hydrogenation.
Our fully equipped high-pressure lab is designed to take your ideas from concept to kilo scale with maximum flexibility and safety:
- Miniplants with autoclaves up to 5 liters
- 24h / 5-day operations, in both batch and continuous mode
- Lab-scale campaigns with outputs up to 10 kg
- Pressure range: up to 300 bar
- Temperature capability: up to 300 °C
Our dedicated hydrogenation units enable safe, scalable, and sustainable production — including the use of green hydrogen:
- Batch production lines operating at temperatures up to 320 °C and pressures up to 200 bar H₂
- Batch-continuous hybrid line operating at temperatures up to 220 °C and up to 200 bar H₂
- Integrated distillation systems for efficient post-hydrogenation work-up and purification
Tailored solutions for your synthesis challenges.
Saltigo’s experienced teams provide custom process design and scale-up support across a wide range of hydrogenation transformations, including:
- Nitro compound reductions
- Hydrogenation of aromatic rings
- Reduction of aldehydes, ketones, imines, and nitriles
- Reductive amination
- Reduction of double/triple bonds
- Reductive alkylation
Chlorination at Saltigo
Saltigo offers deep expertise and robust capabilities in the production and processing of chlorinated organic intermediates, serving a wide range of applications in the chemical and pharmaceutical industries. Our dedicated infrastructure and process know-how enable efficient, safe, and scalable solutions for demanding chlorination steps.
Saltigo’s production environment is equipped to meet a wide range of technical and regulatory requirements — enabling customized and scalable manufacturing solutions.
- Multiple reaction lines for complex multistep syntheses
- Stirred tank reactors from 6 to 16 m³, made of Hastelloy, glass-lined steel and stainless steel
- Diverse distillation units, including a dividing-wall column for energy-efficient separations
- Chlorine supply infrastructure for safe and continuous operations
- Solid handling via powder transfer systems (PTS) for contained dosing of solid raw materials
- Post-processing equipment, such as pressure nutsches, for solid-liquid separation
- Loading and unloading of liquids via pipe bridges, containers, or small packaging units
- Drum-filling station for safe and efficient product shipment
- Chlorination with PCl₃/Cl₂ in POCl₃
Performed in a dedicated plant to ensure maximum process safety and consistent quality - Synthesis of aryl ethers
Based on chlorophenols and chlorinated benzene derivatives via Ullmann coupling - Electrophilic ring chlorination of aromatic compounds
- Side-chain chlorination of substituted toluenes
- Follow-up chemistry based on side-chain chlorination, including benzoyl chlorides, aldehydes, and other key intermediates
Flexible and safe development of chlorination chemistry.
Saltigo offers broad flexibility in chlorination process development, with the ability to simulate various conditions under controlled laboratory environments:
- Chlorination with chlorine gas can be safely performed in our process development laboratories
- Alternative chlorination reagents — such as PCl₃, POCl₃, PCl₅, cyanuric chloride, SOCl₂, SO₂Cl₂, COCl₂, and oxalyl chloride — are also routinely handled
- Pressurized chlorination reactions (e.g., required for certain heteroaromatic compounds) can be carried out in our high pressure laboratories